Nachtlens drukt bijziend kinderoog in het gareel

Orthokeratology for myopic control: Clinical performance of two hyper DK reverse geometry lenses (spherical and toric designs) used in the ROMIO and TO-SEE studies

Pauline Cho
Peggy Cheung
Connie Chen

PURPOSE
To report the clinical performance of two hyper DK reverse geometry lenses used in the ROMIO* and TO-SEE* studies for myopic control in children.

METHOD
Children who satisfied the inclusion criteria of the ROMIO (6-10 yo, myopia 4.00D or less, WTR astigmatism 1.25D or less) and TO-SEE (6-10 yo, myopia 5.00D or less, WTR astigmatism 1.25-3.00D) studies were fitted with Menicon Z Night Lens (ROMIO, spherical design) and Menicon Z Night Toric (TO-SEE, toric design) using the Easy Fit software provided by the manufacturer. Clinical performance was evaluated after one-month lens wear.

RESULTS
Fifty-one myopic children, randomly assigned to the orthokeratology group, were fitted with Menicon Z Night lenses in the ROMIO study. About 90% of the children were successfully fitted with the first pair of lenses and eight of them under-responded (SER>0.50D) and needed a second pair of lenses with increased target after one week of lens wear. One child had residual spherical equivalent refraction of over 0.50D despite increased target and was excluded from the study. Unaided VA of the right eye of these children was 0.03+/-0.10 logMAR after one-month lens wear.
Forty four myopic astigmatic children were fitted with Menicon Z Night Toric lenses in the TO-SEE study. About 95% of the children were successfully fitted with the first pair of lenses. At the one-month visit, unaided VA of the right eye of these children was 0.11+/-0.15 and a second pair of lenses with increased target were ordered for two children who under-responded.
No significant adverse effect was observed during the one-month lens wear in both studies. Currently, 88% and 100% of the ROMIO and TO-SEE children respectively are still participating in the studies.

CONCLUSIONS
Results indicated successful first-fit rates of 90% using the Menicon Z Night lenses and 95% using the Menicon Z Night Toric lenses. Refitting was required for about 17% and 5% of these children respectively due to under-responding and only one child continued to under-respond despite lens modifcation.
(*Retardation Of Myopia In Orthokeratology (ROMIO) study and Toric Orthokeratology – Slowing Eyeball Elongation (TO-SEE) study are supported by Collaborative Research Agreements between PolyU and Menicon Co. Ltd., Japan.)